TRH antibody (Center)
Quick Overview for TRH antibody (Center) (ABIN2795323)
Target
See all TRH AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 209-238, Center
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Purpose
- Rabbit Anti-Human TRHR (Center) Antibody
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Immunogen
- This TRHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-238 amino acids from the Central region of human TRHR.
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Isotype
- Ig Fraction
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Application Notes
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Western Blot
Recommended Dilutions
WB: 1:1000TRHR Antibody (Center) . -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.350 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- TRH (Thyrotropin-Releasing Hormone (TRH))
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Alternative Name
- TRH
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Background
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Target Description: Thyrotropin-releasing hormone (TRH, MIM 275120), a small neuropeptide, is widely distributed throughout the central and peripheral nervous system as well as in extraneural tissues. The peptide is synthesized in the hypothalamus and transported by the portal vascular system to the anterior pituitary where it acts on thyrotropic and lactotropic cells to promote secretion of TSH and prolactin, respectively. Thyrotropin-releasing hormone receptor is a G protein-coupled receptor that activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon the binding of TRH. The TRHR gene is expressed in the thyrotrope cells of the anterior pituitary.
Gene Symbol: TRHR
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Molecular Weight
- 45085 Da
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Gene ID
- 7201
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UniProt
- P34981
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Pathways
- Positive Regulation of Peptide Hormone Secretion, Feeding Behaviour
Target
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