MBP antibody (AA 177-209)

Catalog No. ABIN2796440

The Rabbit Polyclonal anti-MBP antibody has been validated for WB. It is suitable to detect MBP in samples from Human.

Quick Overview for MBP antibody (AA 177-209) (ABIN2796440)

Target: MBP (Myelin Basic Protein (MBP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MBP Antibody

Binding Specificity: AA 177-209

Purpose: Rabbit Anti-Human MBP (Y203) Antibody

Immunogen: This MBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-209 amino acids from human MBP.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of anti-MBP Antibody (Y203) was detected using the purified Pab.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.370 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for MBP

Target: MBP (Myelin Basic Protein (MBP))

Alternative Name: Myelin basic protein

Background:

Target Description: MBP is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called Golli-MBP) that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.

Gene Symbol: MBP

Molecular Weight: 33117 Da

Gene ID: 4155

UniProt: P02686