LIM Domain Kinase 1 antibody (C-Term)
Quick Overview for LIM Domain Kinase 1 antibody (C-Term) (ABIN2796575)
Target
See all LIM Domain Kinase 1 (LIMK1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 479-508, C-Term
-
Purpose
- Mouse Anti-Mouse LIMK1 (C-term) Antibody
-
Immunogen
- This LIMK1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 479-508 amino acids from the C-terminal region of human LIMK1.
-
Isotype
- IgG1 kappa
-
-
-
-
Application Notes
-
Western Blot
Recommended Dilutions
WB: 1:100-1000LIMK1 Antibody (C-term) . -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- 2-8°C (short-term), -20°C (long-term)
-
-
- LIM Domain Kinase 1 (LIMK1)
-
Alternative Name
- LIMK1
-
Background
-
Target Description: Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.
Gene Symbol: LIMK1
-
Molecular Weight
- 72585 Da
-
Gene ID
- 3984
-
UniProt
- P53667
-
Pathways
- Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
Target
-