EGF antibody (C-Term)

Catalog No. ABIN2796844

This Mouse Monoclonal antibody specifically detects EGF in WB. It exhibits reactivity toward Human.

Quick Overview for EGF antibody (C-Term) (ABIN2796844)

Target: EGF (Epidermal Growth Factor (EGF))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EGF antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EGF Antibody

Binding Specificity: AA 1163-1191, C-Term

Purpose: Mouse Anti-Human EGFR (C-term) Antibody

Immunogen: This EGFR antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1163-1191 amino acids from the C-terminal region of human EGFR.

Isotype: IgG1

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000EGFR Antibody (C-term) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.500 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for EGF

Target: EGF (Epidermal Growth Factor (EGF))

Alternative Name: EGF

Background:

Target Description: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Gene Symbol: EGFR

Molecular Weight: 134277 Da

Gene ID: 1956

UniProt: P00533

Pathways: NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation