Complement Factor H antibody (Center)

Catalog No. ABIN2797150

This Rabbit Polyclonal antibody specifically detects Complement Factor H in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for Complement Factor H antibody (Center) (ABIN2797150)

Target: Complement Factor H (CFH)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Complement Factor H antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Complement Factor H Antibody

Binding Specificity: AA 751-780, Center

Purpose: Rabbit Anti-Human CFH (Center) Antibody

Immunogen: This CFH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human CFH.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100, IF: 1:10-50CFH Antibody (Center) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.287 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for Complement Factor H

Target: Complement Factor H (CFH)

Alternative Name: CFH

Background:

Target Description: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Symbol: CFH

Molecular Weight: 139096 Da

Gene ID: 3075

UniProt: P08603

Pathways: Complement System, Cellular Response to Molecule of Bacterial Origin