MLH1 antibody (Center)

Catalog No. ABIN2797430

The Rabbit Polyclonal anti-MLH1 antibody is suitable to detect MLH1 in samples from Human. It has been validated for WB and FACS.

Quick Overview for MLH1 antibody (Center) (ABIN2797430)

Target: MLH1 (MutL Homolog 1 (MLH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLH1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-MLH1 Antibody

Binding Specificity: AA 452-480, Center

Purpose: Rabbit Anti-Human MLH1 (Center) Antibody

Immunogen: This MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-480 amino acids from the Central region of human MLH1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Flow Cytometry
Recommended Dilutions
WB: 1:1000, FC: 1:10-50MLH1 Antibody (Center) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.400 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for MLH1

Target: MLH1 (MutL Homolog 1 (MLH1))

Alternative Name: MLH1

Background:

Target Description: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

Gene Symbol: MLH1

Molecular Weight: 84601 Da

Gene ID: 4292

UniProt: P40692

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response