Surfactant Protein C antibody (N-Term)

Catalog No. ABIN2797711

This Rabbit Polyclonal antibody specifically detects Surfactant Protein C in WB and IF. It exhibits reactivity toward Mouse.

Quick Overview for Surfactant Protein C antibody (N-Term) (ABIN2797711)

Target: Surfactant Protein C (SFTPC)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Surfactant Protein C antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Surfactant Protein C Antibody

Binding Specificity: AA 1-30, N-Term

Purpose: Rabbit Anti-Mouse SFTPC (N-term) Antibody

Immunogen: This SFTPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SFTPC.

Isotype: Ig Fraction

Application Details

Application Notes: Immunofluorescence, Western Blot
Recommended Dilutions
IF: 1:25, WB: 1:1000Immunofluorescent analysis of Human lung tissues, using SFTPC Antibody (N-term) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.340 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for Surfactant Protein C

Target: Surfactant Protein C (SFTPC)

Alternative Name: SFTPC

Background:

Target Description: This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Gene Symbol: SFTPC

Molecular Weight: 21053 Da

Gene ID: 6440

UniProt: P11686