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Surfactant Protein C antibody

SFTPC Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7259843
  • Target See all Surfactant Protein C (SFTPC) Antibodies
    Surfactant Protein C (SFTPC)
    Reactivity
    • 57
    • 36
    • 27
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 67
    • 8
    Rabbit
    Clonality
    • 69
    • 6
    Polyclonal
    Conjugate
    • 30
    • 9
    • 8
    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Surfactant Protein C antibody is un-conjugated
    Application
    • 50
    • 41
    • 30
    • 27
    • 16
    • 15
    • 13
    • 13
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human SFTPC (NP_001165881.1).
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Surfactant Protein C (SFTPC)
    Alternative Name
    SFTPC (SFTPC Products)
    Synonyms
    SFTPC antibody, SPC antibody, SP-C antibody, psp-c antibody, sftp2 antibody, xSP-C antibody, Bricd6 antibody, SP5 antibody, Sftp-2 antibody, Sftp2 antibody, pro-SpC antibody, BRICD6 antibody, PSP-C antibody, SFTP2 antibody, SMDP2 antibody, surfactant protein C antibody, surfactant, pulmonary-associated protein C S homeolog antibody, surfactant, pulmonary-associated protein C antibody, surfactant associated protein C antibody, SFTPC antibody, sftpc.S antibody, sftpc antibody, Sftpc antibody
    Background
    This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
    Molecular Weight

    Observed_MW: 21 kDa

    Calculated_MW: 20 kDa/21 kDa

    Gene ID
    6440
    UniProt
    P11686
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