MYBPC3 antibody (N-Term)

Catalog No. ABIN2797756

This Rabbit Polyclonal antibody specifically detects MYBPC3 in WB and IHC. It exhibits reactivity toward Mouse.

Quick Overview for MYBPC3 antibody (N-Term) (ABIN2797756)

Target: MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYBPC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MYBPC3 Antibody

Binding Specificity: AA 189-218, N-Term

Purpose: Rabbit Anti-Mouse MYBPC3 (N-term) Antibody

Immunogen: This MYBPC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the N-terminal region of human MYBPC3.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50MYBPC3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.500 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for MYBPC3

Target: MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

Alternative Name: MYBPC3

Background:

Target Description: MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.

Gene Symbol: MYBPC3

Molecular Weight: 140762 Da

Gene ID: 4607

UniProt: Q14896