CDH6 antibody (C-Term)

Catalog No. ABIN2798460

This anti-CDH6 antibody is a Rabbit Polyclonal antibody detecting CDH6 in WB, IHC and FACS. Suitable for Human.

Quick Overview for CDH6 antibody (C-Term) (ABIN2798460)

Target: CDH6 (K-Cadherin (CDH6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDH6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-CDH6 Antibody

Binding Specificity: AA 665-695, C-Term

Purpose: Rabbit Anti-Human K Cadherin (CDH6) (C-term) Antibody

Immunogen: This K Cadherin (CDH6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-695 amino acids from the C-terminal region of human K Cadherin (CDH6).

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, FC: 1:10-50Western blot analysis of anti-DH6 Antibody (C-term) (RB14082) in 293 cell line lysates (35 μg/lane). DH6(arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CDH6 antibody (C-term) . FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for CDH6

Target: CDH6 (K-Cadherin (CDH6))

Alternative Name: K Cadherin

Background:

Target Description: CDH6 is a type II classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion membrane glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of the CDH6 gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.

Gene Symbol: CDH6

Molecular Weight: 88309 Da

Gene ID: 1004

UniProt: P55285

Pathways: Cell-Cell Junction Organization