Cytohesin 1 antibody (N-Term)

Catalog No. ABIN2798479

This Rabbit Polyclonal antibody specifically detects Cytohesin 1 in WB. It exhibits reactivity toward Human.

Quick Overview for Cytohesin 1 antibody (N-Term) (ABIN2798479)

Target: Cytohesin 1 (CYTH1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytohesin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cytohesin 1 Antibody

Binding Specificity: AA 37-65, N-Term

Purpose: Rabbit Anti-Human CYTH1 (N-term) Antibody

Immunogen: This CYTH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human CYTH1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000CYTH1 Antibody (N-term) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for Cytohesin 1

Target: Cytohesin 1 (CYTH1)

Alternative Name: CYTH1

Background:

Target Description: The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83 % homologous to that of CYTH2.

Gene Symbol: CYTH1

Molecular Weight: 46413 Da

Gene ID: 9267

UniProt: Q15438