CSTB antibody (Center)

Catalog No. ABIN2798556

This anti-CSTB antibody is a Rabbit Polyclonal antibody detecting CSTB in WB. Suitable for Human.

Quick Overview for CSTB antibody (Center) (ABIN2798556)

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSTB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CSTB Antibody

Binding Specificity: AA 10-39, Center

Purpose: Rabbit Anti-Human CSTB (Center) Antibody

Immunogen: This CSTB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the Central region of human CSTB.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000CSTB Antibody (Center) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for CSTB

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Alternative Name: CSTB

Background:

Target Description: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).

Gene Symbol: CSTB

Molecular Weight: 11140 Da

Gene ID: 1476

UniProt: P04080

Pathways: Response to Water Deprivation