Cyclin D2 antibody (N-Term)

Catalog No. ABIN2798589

This anti-Cyclin D2 antibody is a Rabbit Polyclonal antibody detecting Cyclin D2 in WB. Suitable for Human.

Quick Overview for Cyclin D2 antibody (N-Term) (ABIN2798589)

Target: Cyclin D2 (CCND2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin D2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cyclin D2 Antibody

Binding Specificity: AA 1-30, N-Term

Purpose: Rabbit Anti-Human CCND2 (N-term) Antibody

Immunogen: This CCND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCND2.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000CCND2 Antibody (N-term) with the CCND2 gene.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for Cyclin D2

Target: Cyclin D2 (CCND2)

Alternative Name: CCND2

Background:

Target Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.

Gene Symbol: CCND2

Molecular Weight: 33067 Da

Gene ID: 894

UniProt: P30279

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases