HNMT antibody (N-Term)

Catalog No. ABIN2798592

This anti-HNMT antibody is a Rabbit Polyclonal antibody detecting HNMT in WB, IHC and IF. Suitable for Human.

Quick Overview for HNMT antibody (N-Term) (ABIN2798592)

Target: HNMT (Histamine N-Methyltransferase (HNMT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNMT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-HNMT Antibody

Binding Specificity: AA 29-58, N-Term

Purpose: Rabbit Anti-Human HNMT (N-term) Antibody

Immunogen: This HNMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human HNMT.

Isotype: Ig Fraction

Application Details

Application Notes: Immunofluorescence, Western Blot, Immunohistochemistry
Recommended Dilutions
IF: 1:10-50, WB: 1:1000, IHC: 1:10-50Confocal immunofluorescent analysis of HNMT Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.0 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for HNMT

Target: HNMT (Histamine N-Methyltransferase (HNMT))

Alternative Name: HNMT

Background:

Target Description: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. HNMT is the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells.

Gene Symbol: HNMT

Molecular Weight: 33295 Da

Gene ID: 3176

UniProt: P50135