STK39 antibody (C-Term)
Quick Overview for STK39 antibody (C-Term) (ABIN2798612)
Target
See all STK39 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 386-415, C-Term
-
Purpose
- Rabbit Anti-Human SPAK (STK39) (C-term) Antibody
-
Immunogen
- This SPAK (STK39) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-415 amino acids from the C-terminal region of human SPAK (STK39).
-
Isotype
- Ig Fraction
-
-
-
-
Application Notes
-
Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50STK39 Antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 2.0 mg/mL
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- 2-8°C (short-term), -20°C (long-term)
-
-
- STK39 (serine threonine Kinase 39 (STK39))
-
Alternative Name
- SPAK
-
Background
-
Target Description: STK39 is a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.
Gene Symbol: STK39
-
Molecular Weight
- 59474 Da
-
Gene ID
- 27347
-
UniProt
- Q9UEW8
Target
-