RFXAP antibody (C-Term)
Quick Overview for RFXAP antibody (C-Term) (ABIN2798622)
Target
See all RFXAP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 196-225, C-Term
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Purpose
- Rabbit Anti-Human RFXAP (C-term) Antibody
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Immunogen
- This RFXAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-225 amino acids from the C-terminal region of human RFXAP.
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Isotype
- Ig Fraction
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Application Notes
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Western Blot
Recommended Dilutions
WB: 1:1000RFXAP Antibody (C-term) . -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.500 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- RFXAP (Regulatory Factor X-Associated Protein (RFXAP))
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Alternative Name
- RFXAP
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Background
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Target Description: Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene.
Gene Symbol: RFXAP
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Molecular Weight
- 28232 Da
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Gene ID
- 5994
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UniProt
- O00287
Target
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