FOLR2 antibody (N-Term)
Quick Overview for FOLR2 antibody (N-Term) (ABIN2798891)
Target
See all FOLR2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 17-44, N-Term
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Purpose
- Rabbit Anti-Human FOLR2 (N-term) Antibody
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Immunogen
- This FOLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-44 amino acids from the N-terminal region of human FOLR2.
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Isotype
- Ig Fraction
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Application Notes
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Western Blot
Recommended Dilutions
WB: 1:1000FOLR2 Antibody (N-term) . -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.350 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
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Alternative Name
- FOLR2
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Background
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Target Description: The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.
Gene Symbol: FOLR2
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Molecular Weight
- 29280 Da
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Gene ID
- 2350
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UniProt
- P14207
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Pathways
- Dicarboxylic Acid Transport
Target
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