KIDINS220 antibody (C-Term)

Catalog No. ABIN2798982

This anti-KIDINS220 antibody is a Rabbit Polyclonal antibody detecting KIDINS220 in WB. Suitable for Human.

Quick Overview for KIDINS220 antibody (C-Term) (ABIN2798982)

Target: KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIDINS220 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KIDINS220 Antibody

Binding Specificity: AA 1518-1547, C-Term

Purpose: Rabbit Anti-Human KIDINS220 (C-term) Antibody

Immunogen: This KIDINS220 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1518-1547 amino acids from the C-terminal region of human KIDINS220.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000KIDINS220 Antibody (C-term) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for KIDINS220

Target: KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))

Alternative Name: KIDINS220

Background:

Target Description: KIDINS220 promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. May play a role in neurotrophin-and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.

Gene Symbol: KIDINS220

Molecular Weight: 196542 Da

Gene ID: 57498

UniProt: Q9ULH0