LZTS1 antibody (AA 21-120) (AbBy Fluor® 594)

Catalog No. ABIN2803902

The Rabbit Polyclonal anti-LZTS1 antibody is suitable to detect LZTS1 in samples from Human. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for LZTS1 antibody (AA 21-120) (AbBy Fluor® 594) (ABIN2803902)

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZTS1 antibody is conjugated to AbBy Fluor® 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-LZTS1 Antibody (AbBy Fluor® 594)

Binding Specificity: AA 21-120

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LZTS1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LZTS1

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Alternative Name: LZTS1

Background:

Synonyms: F37, F37/esophageal cancer related gene coding leucine zipper mot, Leucine zipper putative tumor suppressor 1, Psdzip70, LZTS1_HUMAN.

Background: This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer. [provided by RefSeq].

Gene ID: 11178

Pathways: Synaptic Membrane