MBP antibody (AA 69-85) (AbBy Fluor® 594)

Catalog No. ABIN2804042

This Rabbit Polyclonal antibody specifically detects MBP in WB, FACS, IF (cc) and IF (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for MBP antibody (AA 69-85) (AbBy Fluor® 594) (ABIN2804042)

Target: MBP

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBP antibody is conjugated to AbBy Fluor® 594

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MBP Antibody (AbBy Fluor® 594)

Binding Specificity: AA 69-85

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Pig,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from Guinea Pig MBP

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MBP

Target: MBP

Background:

Synonyms: MBP_CAVPO,Myelin Basic Protein, Myelin basic protien, GDB, Golli MBP, Hemopoietic MBP, HMBPR, HUGO, MBP, MGC99675, MLD, Myelin A1 Protein, Myelin Deficient, Myelin Membrane Encephalitogenic Protein, SHI, Shiverer, SP, MBP TAG, MBP-TAG

Background: Oligodendrocyte Marker The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.