CDK17 antibody (AA 301-400) (AbBy Fluor® 594)

Catalog No. ABIN2805171

The Rabbit Polyclonal anti-CDK17 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect CDK17 in samples from Sheep.

Quick Overview for CDK17 antibody (AA 301-400) (AbBy Fluor® 594) (ABIN2805171)

Target: CDK17 (Cyclin-Dependent Kinase 17 (CDK17))

Reactivity: Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK17 antibody is conjugated to AbBy Fluor® 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CDK17 Antibody (AbBy Fluor® 594)

Binding Specificity: AA 301-400

Cross-Reactivity: Sheep

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCTAIRE2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CDK17

Target: CDK17 (Cyclin-Dependent Kinase 17 (CDK17))

Alternative Name: PCTAIRE2

Background:

Synonyms: PCTAIRE-2, PCTAIRE-mot protein kinase 2, PCTK2, Protein kinase cdc2-related PCTAIRE-2, Serine/threonine-protein kinase PCTAIRE-2, 6430598J10Rik, EC 2.7.1.37, MGC25109, CDK17_HUMAN.

Background: Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with cyclins to phosphorylate key substrates involved in cell cycle progression. Another family of proteins, Cdk inhibitors, also play a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Members of the Cdk family include Cdk2Cdk8, PCTAIRE-13, PITALRE and PITSLRE. PCTAIRE-1, PCTAIRE-2 and PCTAIRE-3 comprise a subfamily of cdc2-related serine/threonine kinases. PCTAIRE-1, which is expressed primarily in mammalian brain, interacts with a variety of proteins and is thought to be part of a multiple signal transduction cascade. PCTAIRE-2, also expressed in brain, may be important in terminally differentiated neurons.