PITX3 antibody (AA 231-302) (AbBy Fluor® 594)

Catalog No. ABIN2805359

This anti-PITX3 antibody is a Rabbit Polyclonal antibody detecting PITX3 in WB, IF (cc) and IF (p). Suitable for Mouse, Rat and Cow.

Quick Overview for PITX3 antibody (AA 231-302) (AbBy Fluor® 594) (ABIN2805359)

Target: PITX3 (Pituitary Homeobox 3 (PITX3))

Reactivity: Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PITX3 antibody is conjugated to AbBy Fluor® 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PITX3 Antibody (AbBy Fluor® 594)

Binding Specificity: AA 231-302

Cross-Reactivity: Cow, Mouse, Rat

Predicted Reactivity: Human,Dog,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PITX3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PITX3

Target: PITX3 (Pituitary Homeobox 3 (PITX3))

Alternative Name: PITX3

Background:

Synonyms: Homeobox protein PITX 3, Homeobox protein PITX3, MGC12766, Paired like homeodomain transcription factor 3, Paired-like homeodomain transcription factor 3, Pituitary homeobox 3, PITX 3, Pitx3, PITX3_HUMAN, PTX 3, PTX3.

Background: The transcription factor PITX3 is expressed selectively in the midbrain and regulates the differentiation and survival of dopaminergic neurons. Lack of this factor results in a degeneration similar to that seen in Parkinson's disease. PITX3 is also important in eye developement, mutations of the PITX3 gene have been associated with a familial form of cataracts.

Gene ID: 5309