CPSF3L antibody (AA 151-250) (Biotin)

Catalog No. ABIN2808205

The Rabbit Polyclonal anti-CPSF3L antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect CPSF3L in samples from Mouse and Rat.

Quick Overview for CPSF3L antibody (AA 151-250) (Biotin) (ABIN2808205)

Target: CPSF3L (Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPSF3L antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CPSF3L Antibody (Biotin)

Binding Specificity: AA 151-250

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Horse,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human INT11

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CPSF3L

Target: CPSF3L (Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L))

Alternative Name: INT11

Background:

Synonyms: RC68, INT11, RC-68, INTS11, CPSF73L, Integrator complex subunit 11, Cleavage and polyadenylation-specific factor 3-like protein, CPSF3-like protein, Protein related to CPSF subunits of 68 kDa, CPSF3L

Background: Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage.

Gene ID: 54973

UniProt: Q5TA45