CPSF3L antibody (AA 331-600)

Catalog No. ABIN6138970

Product Details anti-CPSF3L Antibody

Target: CPSF3L (Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L))

Binding Specificity: AA 331-600

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPSF3L antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequence: GQSLQIFRKW AGNEKNMVIM PGYCVQGTVG HKILSGQRKL EMEGRQVLEV KMQVEYMSFS AHADAKGIMQ LVGQAEPESV LLVHGEAKKM EFLKQKIEQE LRVNCYMPAN GETVTLPTSP SIPVGISLGL LKREMAQGLL PEAKKPRLLH GTLIMKDSNF RLVSSEQALK ELGLAEHQLR FTCRVHLHDT RKEQETALRV YSHLKSVLKD HCVQHLPDGS VTVESVLLQA AAPSEDPGTK VLLVSWTYQD EELGSFLTSL LKKGLPQAPS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 331-600 of human CPSF3L (NP_060341.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:10 - 1:100,IP,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CPSF3L

Target: CPSF3L (Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L))

Alternative Name: CPSF3L (CPSF3L Products)

Synonyms: DDBDRAFT_0204486 antibody, DDBDRAFT_0234100 antibody, DDB_0204486 antibody, DDB_0234100 antibody, int11 antibody, CPSF73L antibody, INT11 antibody, INTS11 antibody, RC-68 antibody, RC68 antibody, 2410006F12Rik antibody, AU044035 antibody, RGD1306841 antibody, zgc:110671 antibody, CPSF3L antibody, DKFZp469C1432 antibody, cleavage and polyadenylation specific factor 3-like antibody, integrator complex subunit 11 antibody, RNA-metabolising metallo-beta-lactamase domain-containing protein antibody, microRNA 6727 antibody, CPSF3L antibody, INTS11 antibody, ints11 antibody, Ints11 antibody, MIR6727 antibody

Background: The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008],INTS11,CPSF3L,CPSF73L,INT11,RC-68,RC68,Epigenetics & Nuclear Signaling,CPSF3L

Molecular Weight: 56 kDa/64 kDa/65 kDa/67 kDa/68 kDa

Gene ID: 54973

UniProt: Q5TA45