STAMBP antibody (AA 331-420) (AbBy Fluor® 594)

Catalog No. ABIN2809704

This Rabbit Polyclonal antibody specifically detects STAMBP in IF (cc) and IF (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for STAMBP antibody (AA 331-420) (AbBy Fluor® 594) (ABIN2809704)

Target: STAMBP (STAM Binding Protein (STAMBP))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAMBP antibody is conjugated to AbBy Fluor® 594

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-STAMBP Antibody (AbBy Fluor® 594)

Binding Specificity: AA 331-420

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AMSH

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for STAMBP

Target: STAMBP (STAM Binding Protein (STAMBP))

Alternative Name: AMSH

Background:

Synonyms: Associated molecule with the SH3 domain of STAM, Endosome associated ubiquitin isopeptidase, Endosome-associated ubiquitin isopeptidase, STABP_HUMAN, STAM binding protein, STAM-binding protein, STAMBP.

Background: Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Functions at the endosome and is able to oppose the ubiquitin-dependent sorting of receptors to lysosomes. Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7.

Gene ID: 10617