The Rabbit Polyclonal anti-HIST1H2AG antibody has been validated for WB. It is suitable to detect HIST1H2AG in samples from Human and Mouse. There are 5+ publications available.
This HIST1H2AG antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 63-87 amino acids from the Central region of human HIST1H2AG.
HIST1H2AG
Reactivity: Human
ELISA, IF, ICC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB: 1:2000
Restrictions
For Research Use only
Format
Liquid
Storage
4 °C,-20 °C
Expiry Date
6 months
Marzluff, Gongidi, Woods, Jin, Maltais: "The human and mouse replication-dependent histone genes." in: Genomics, Vol. 80, Issue 5, pp. 487-98, (2002) (PubMed).
Albig, Trappe, Kardalinou, Eick, Doenecke: "The human H2A and H2B histone gene complement." in: Biological chemistry, Vol. 380, Issue 1, pp. 7-18, (1999) (PubMed).
Albig, Doenecke: "The human histone gene cluster at the D6S105 locus." in: Human genetics, Vol. 101, Issue 3, pp. 284-94, (1998) (PubMed).
Mannironi, Orr, Hatch, Pilch, Ivanova, Bonner: "The relative expression of human histone H2A genes is similar in different types of proliferating cells." in: DNA and cell biology, Vol. 13, Issue 2, pp. 161-70, (1994) (PubMed).
Dobner, Wolf, Mai, Lipp: "A novel divergently transcribed human histone H2A/H2B gene pair." in: DNA sequence : the journal of DNA sequencing and mapping, Vol. 1, Issue 6, pp. 409-13, (1992) (PubMed).
Target
HIST1H2AG
(Histone Cluster 1, H2ag (HIST1H2AG))
Alternative Name
HIST1H2AG
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.