Complement C3b antibody

Catalog No. ABIN284069

The Mouse Monoclonal anti-Complement C3b antibody has been validated for WB and IHC (fro). It is suitable to detect Complement C3b in samples from Human. There is 1 publication available.

Quick Overview for Complement C3b antibody (ABIN284069)

Target: Complement C3b (C3b) (Complement C3 beta Chain (C3b))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Complement C3b antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: H11

Product Details anti-Complement C3b Antibody

Immunogen: Complement C3 b beta antibody was raised in mouse using human complement component C3 as the immunogen.

Isotype: IgG1

Application Details

Application Notes: IHC-F: 1:10
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in dist. water (final solution contains 0.09 % NaN3, 0.5 % BSA in PBS buffer, pH 7.4)

Concentration: Lot specific

Buffer: Supplied as a lyophilized powder.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

References for anti-Complement C3b antibody (ABIN284069)

Premanandan, Storozuk, Clay, Lairmore, Schlesinger, Phipps: "Complement protein C3 binding to Bacillus anthracis spores enhances phagocytosis by human macrophages." in: Microbial pathogenesis, Vol. 46, Issue 6, pp. 306-14, (2009) (PubMed).

Target Details for Complement C3b

Target: Complement C3b (C3b) (Complement C3 beta Chain (C3b))

Alternative Name: Complement C3b beta

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling