C10orf2 antibody (C-Term)
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- Target See all C10orf2 (C10ORF2) Antibodies
- C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))
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Binding Specificity
- AA 656-684, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This C10orf2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This C10orf2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 656-684 amino acids from the C-terminal region of human C10orf2.
- Clone
- RB32016
- Isotype
- Ig Fraction
- Top Product
- Discover our top product C10ORF2 Primary Antibody
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- Application Notes
- WB: 1:1000. IHC-P: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- C10orf2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Expiry Date
- 6 months
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- Target
- C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))
- Alternative Name
- C10orf2 (C10ORF2 Products)
- Background
- This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Molecular Weight
- 77154
- Gene ID
- 56652
- NCBI Accession
- NP_001157284, NP_068602
- UniProt
- Q96RR1
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