CGB antibody (C-Term)

Catalog No. ABIN2846144

The Rabbit Polyclonal anti-CGB antibody has been validated for WB and IHC (p). It is suitable to detect CGB in samples from Human. There is 1 publication available.

Quick Overview for CGB antibody (C-Term) (ABIN2846144)

Target: CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CGB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB32849

Product Details anti-CGB Antibody

Binding Specificity: AA 137-165, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CGB/HCG-Beta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-165 amino acids from the C-terminal region of human CGB/HCG-Beta.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CGB/HCG-Alpha/Beta Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.Precaut.

Expiry Date: 6 months

References for anti-CGB antibody (ABIN2846144)

Liu, Peng, Zhan, Yu, Wu, Gao, Li, Guo: "Human chorionic gonadotropin β regulates epithelial-mesenchymal transition and metastasis in human ovarian cancer." in: Oncology reports, Vol. 38, Issue 3, pp. 1464-1472, (2018) (PubMed).

Target Details for CGB

Target: CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))

Alternative Name: CGB/HCG-Alpha/Beta

Background: This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.

Molecular Weight: 17739

Gene ID: 94115, 94027, 93659

NCBI Accession: NP_000728, NP_149032, NP_149133, NP_149439

UniProt: P0DN86