Troponin I antibody (AA 186-192)

Catalog No. ABIN284801

The Mouse Monoclonal anti-Troponin I antibody has been validated for WB, ELISA, IHC and IP. It is suitable to detect Troponin I in samples from Human. There are 5+ publications available.

Quick Overview for Troponin I antibody (AA 186-192) (ABIN284801)

Target: Troponin I (TNNI)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Troponin I antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: C5

Product Details anti-Troponin I Antibody

Binding Specificity: AA 186-192

Purification: purified

Immunogen: Troponin I antibody (cardiac) was raised in mouse using amino acid residues 186-192 of cTnI as the immunogen.

Isotype: IgG2b

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Protein A purified and supplied in PBS, pH 7.4, 0.1 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C

References for anti-Troponin I antibody (ABIN284801)

Lin, Schmidt, Fritz, Jeong, Cammarato, Foster, Biesiadecki, McKinsey, Woulfe: "Site-specific acetyl-mimetic modification of cardiac troponin I modulates myofilament relaxation and calcium sensitivity." in: Journal of molecular and cellular cardiology, Vol. 139, pp. 135-147, (2020) (PubMed).

Waas, Weerasekera, Kropp, Romero-Tejeda, Poon, Boheler, Burridge, Gundry: "Are These Cardiomyocytes? Protocol Development Reveals Impact of Sample Preparation on the Accuracy of Identifying Cardiomyocytes by Flow Cytometry." in: Stem cell reports, Vol. 12, Issue 2, pp. 395-410, (2020) (PubMed).

Woulfe, Ferrara, Pioner, Mahaffey, Coppini, Scellini, Ferrantini, Piroddi, Tesi, Poggesi, Jeong: "A Novel Method of Isolating Myofibrils From Primary Cardiomyocyte Culture Suitable for Myofibril Mechanical Study." in: Frontiers in cardiovascular medicine, Vol. 6, pp. 12, (2019) (PubMed).

Lin, Warren, Li, McKinsey, Russell: "Myofibril growth during cardiac hypertrophy is regulated through dual phosphorylation and acetylation of the actin capping protein CapZ." in: Cellular signalling, Vol. 28, Issue 8, pp. 1015-24, (2017) (PubMed).

Scruggs, Walker, Lyu, Geenen, Solaro, Buttrick, Goldspink: "Partial replacement of cardiac troponin I with a non-phosphorylatable mutant at serines 43/45 attenuates the contractile dysfunction associated with PKCepsilon phosphorylation." in: Journal of molecular and cellular cardiology, Vol. 40, Issue 4, pp. 465-73, (2006) (PubMed).

Target Details for Troponin I

Target: Troponin I (TNNI)

Alternative Name: Troponin I