CD300a antibody (FITC)

Catalog No. ABIN2853603

The Rat Monoclonal anti-CD300a antibody has been validated for FACS. It is suitable to detect CD300a in samples from Mouse.

Quick Overview for CD300a antibody (FITC) (ABIN2853603)

Target: CD300a (CD300A)

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD300a antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: TX40

Product Details anti-CD300a Antibody (FITC)

Specificity: This antibody reacts with mouse CD300a antigen.

Purification: Mouse MAIR-I transfected Ba/F3 cells

Immunogen: Mouse MAIR-I transfected Ba/F3 cells

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, 0.09 % NaN3, 1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8 °C.

Target Details for CD300a

Target: CD300a (CD300A)

Alternative Name: CD300A / CMRF35H

Background: Immune responses are regulated by opposing positive and negative signals triggered by the interaction of activating and inhibitory cell surface receptors with their ligands. Shibuya et al. identified novel paired activated and inhibitory immunoglobulin-like receptors, designated myeloid-associated immunoglobulin-like receptor (MAIR) I and MAIR-II, whose extracellular domains are highly conserved by each other. MAIR-I, expressed on the majority of myeloid cells, including macrophages, granulocytes, mast cells, and dendritic cells, contains the tyrosine-based sorting motif and the immunoreceptor tyrosine-based inhibitory motif-like sequences in the cytoplasmic domains. On the other hand, MAIR-II, expressed on subsets of peritoneal macrophages and B cells, associates with the immunoreceptor tyrosine-based activation motif-bearing adaptor DAP12. MAIR-I is also known as CD300a/ CMRF-35-like Ig-like molecule-8 (CLM-8)/leukocyte mono-Ig-like receptor 1 (LMIR1). MAIR-II is also known as CD300d/LMIR2/CLM-4/dendritic cell-derived Ig-like receptor 1 (DIgR1).Synonyms: CD300 antigen-like family member A, CLM-8, CMRF-35-H9, CMRF35-H, CMRF35-H9, CMRF35-like molecule 8, IRC1/IRC2, IRp60, Inhibitory receptor protein 60, NK inhibitory receptor

Gene ID: 217303

NCBI Accession: NP_739564

UniProt: Q6SJQ0

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process