Podoplanin antibody (FITC)

Catalog No. ABIN2853606

The Rat Monoclonal anti-Podoplanin antibody has been validated for FACS. It is suitable to detect Podoplanin in samples from Mouse.

Quick Overview for Podoplanin antibody (FITC) (ABIN2853606)

Target: Podoplanin (PDPN)

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Podoplanin antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: 8F11

Product Details anti-Podoplanin Antibody (FITC)

Specificity: This antibody reacts with mouse Aggrus/Podoplanin.

Purification: Protein G agarose

Immunogen: NL-17 cell membrane fraction

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, 0.09 % NaN3, 1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8 °C.

Target Details for Podoplanin

Target: Podoplanin (PDPN)

Alternative Name: Podoplanin

Background: In addition to hemostasis and host defense, platelets are involved in the induction of inflammation, tissue repair, and tumor metastasis. Aggrus (T1α/Podoplanin) is a novel 36-45 kDa membrane sialoglycoprotein that induces platelet aggregation. Aggrus is highly expressed in various tumor cells and the platelet aggregation ability of Aggrus depends on specific oligosaccharide structures that may be related to the metastasis process in cancer cells. Aggrus has been identified as a diagnostic tumor marker for seminoma and testicular cancers.Synonyms: Aggrus, GP36, Glycoprotein 36, PA2.26 antigen, PDPN, PSEC0003, PSEC0025, T1-alpha

Gene ID: 10630

NCBI Accession: NP_001006625

UniProt: Q86YL7

Pathways: Dicarboxylic Acid Transport