FZD3 antibody (N-Term)

Catalog No. ABIN2854269

This anti-FZD3 antibody is a Rabbit Polyclonal antibody detecting FZD3 in WB and IHC. Suitable for Human and Mouse. This Primary Antibody has been cited in 2+ publications.

Quick Overview for FZD3 antibody (N-Term) (ABIN2854269)

Target: FZD3 (Frizzled Family Receptor 3 (FZD3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FZD3 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Xenopus laevis, Xenopus tropicalis, Chicken, Rhesus Monkey, Cow (Bovine)

Cross-Reactivity (Details): Mouse (100 %), Rat (100 %), Xenopus laevis (100 %), Xenopus Tropicalis (100 %), Chicken (100 %), Rhesus Monkey (100 %), Bovine (100 %)

Characteristics: Rabbit Polyclonal antibody to Frizzled 3 (frizzled homolog 3 (Drosophila))
Frizzled 3 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Frizzled 3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Immunohistochemistry Assay-dependent dilution Western blot Assay-dependent dilution Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceImmunohistochemistryAssay-dependent dilution Western blotAssay-dependent dilution

Comment:

Positive Control: Synthetic peptide: 1:8,000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-FZD3 antibody (ABIN2854269)

Liu, Zhang, Xuan, Hu, Li, Zhang, Jin, Jin: "Alkaline Phosphatase Controls Lineage Switching of Mesenchymal Stem Cells by Regulating the LRP6/GSK3β Complex in Hypophosphatasia." in: Theranostics, Vol. 8, Issue 20, pp. 5575-5592, (2018) (PubMed).

Chan, Lin, Lin, Kuo, Thang, Chiu, Yu: "Concordant and discordant regulation of target genes by miR-31 and its isoforms." in: PLoS ONE, Vol. 8, Issue 3, pp. e58169, (2013) (PubMed).

Target Details for FZD3

Target: FZD3 (Frizzled Family Receptor 3 (FZD3))

Alternative Name: Frizzled 3

Background: This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.

Cellular Localization: Membrane, Multi-pass membrane protein

Molecular Weight: 76 kDa

Gene ID: 7976

Pathways: WNT Signaling, Tube Formation