FGF12 antibody

Catalog No. ABIN2854302

This anti-FGF12 antibody is a Rabbit Polyclonal antibody detecting FGF12 in WB. Suitable for Human.

Quick Overview for FGF12 antibody (ABIN2854302)

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FGF12 Antibody

Cross-Reactivity: Mouse

Characteristics: Rabbit Polyclonal antibody to FGF12 (fibroblast growth factor 12)
FGF12 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human FGF12. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.01 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FGF12

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Alternative Name: fibroblast growth factor 12

Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

Cellular Localization: Nucleus

Molecular Weight: 27 kDa

Gene ID: 2257

UniProt: P61328

Pathways: Negative Regulation of Transporter Activity