Optimal conditions should be determined byt he investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
Lot specific
Buffer
Monospecific serum with 0.01 % NaN3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Target
C1q
(Complement Fragment C1q (C1q))
Alternative Name
Complement C1q
Background
The C1q complex is potentially multivalent for attachment to the complement fixation sites of immunoglobulin. The sites are on the CH2 domain of IgG and probably on the CH4 domain of IgM. The appropriate peptide sequence of the complement fixing site might become exposed following complexing of the immunoglobulin, or the sites might always be available, but might require multiple attachment by C1q with critical geometry in order to achieve the necessary avidity.