NFKB2 antibody (C-Term)
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- Target See all NFKB2 Antibodies
- NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NFKB2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Specificity
- GTX101150 specifically recognizes NFkB p100 isoform, but not the cleaved p52 isoform.
- Characteristics
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Rabbit Polyclonal antibody to NFkB p100 (nuclear factor of kappa light polypeptide gene enhancer in B-cells 2)
NFkB p100 antibody [C2C3], C-term - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the C-terminus region of human NFkB p100. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product NFKB2 Primary Antibody
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- Application Notes
- Suggested dilution Reference Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceImmunoprecipitation1:100-1:500* Western blot1:500-1:3000*
- Comment
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Positive Control: A431 , HeLa , HepG2 , NIH-3T3 , *YY-8103
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
- Alternative Name
- NFkB p100 (NFKB2 Products)
- Synonyms
- NF-kappaB2 antibody, lyt antibody, p49 antibody, p49/p100 antibody, p50B antibody, p52 antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 antibody, Nfkb2 antibody
- Background
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NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth. For reviews, see Chen et al. (1999) [PubMed 9895331] and Baldwin (1996) [PubMed 8717528].[supplied by OMIM]
Cellular Localization: Nucleus , Cytoplasm - Molecular Weight
- 97 kDa
- Gene ID
- 4791
- Pathways
- Toll-Like Receptors Cascades
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