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c-FOS antibody (Center)

The Rabbit Polyclonal anti-c-FOS antibody has been validated for WB. It is suitable to detect c-FOS in samples from Human.
Catalog No. ABIN2854313

Quick Overview for c-FOS antibody (Center) (ABIN2854313)

Target

See all c-FOS (c-Fos) Antibodies
c-FOS (c-Fos) (c-Fos)

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This c-FOS antibody is un-conjugated

Application

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Western Blotting (WB)
  • Binding Specificity

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    Center

    Cross-Reactivity

    Chimpanzee

    Cross-Reactivity (Details)

    Chimpanzee (100 %)

    Characteristics

    Rabbit Polyclonal antibody to c-Fos (FBJ murine osteosarcoma viral oncogene homolog)
    c-Fos antibody

    Purification

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human c-Fos. The exact sequence is proprietary.

    Isotype

    IgG
  • Application Notes

    Suggested dilution Reference Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:1000-1:10000*

    Comment

    Positive Control: MCF-7 treat 500nM PMA 0.5hr , MCF-7 treat 500nM PMA 1hr , MCF-7 treat 500nM PMA 2hr

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    Preservative

    Thimerosal (Merthiolate)

    Precaution of Use

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    c-FOS (c-Fos) (c-Fos)

    Alternative Name

    C-Fos

    Background

    The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

    Cellular Localization: Nucleus

    Molecular Weight

    41 kDa

    Gene ID

    2353

    Pathways

    S100 Proteins
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