CLTA antibody

Catalog No. ABIN2854366

This Rabbit Polyclonal antibody specifically detects CLTA in WB. It exhibits reactivity toward Human.

Quick Overview for CLTA antibody (ABIN2854366)

Target: CLTA (Clathrin, Light Chain A (CLTA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLTA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CLTA Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to CLTA (clathrin, light chain (Lca))
CLTA antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CLTA. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A549 , mouse brain , rat brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CLTA

Target: CLTA (Clathrin, Light Chain A (CLTA))

Alternative Name: clathrin light chain A

Background: Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants.

Cellular Localization: Cytoplasmic vesicle membrane , Membrane , coated pit

Molecular Weight: 27 kDa

Gene ID: 1211

UniProt: P09496

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation