TADA3L antibody (C-Term)

Catalog No. ABIN2854371

This anti-TADA3L antibody is a Rabbit Polyclonal antibody detecting TADA3L in WB. Suitable for Human.

Quick Overview for TADA3L antibody (C-Term) (ABIN2854371)

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TADA3L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TADA3L Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to TADA3L (transcriptional adaptor 3 (NGG1 homolog, yeast)-like)
TADA3L antibody [C1C3]

Purification: Affinity purified by Protein A.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human TADA3L. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: TADA3L transfected 293T

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 9.46 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TADA3L

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Alternative Name: transcriptional adaptor 3

Background: Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.

Cellular Localization: Nucleus

Molecular Weight: 49 kDa

Gene ID: 10474

UniProt: O75528

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway