ABL2 antibody (Center)

Catalog No. ABIN2854440

This anti-ABL2 antibody is a Rabbit Polyclonal antibody detecting ABL2 in WB. Suitable for Human.

Quick Overview for ABL2 antibody (Center) (ABIN2854440)

Target: ABL2

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ABL2 Antibody

Binding Specificity: Center

Cross-Reactivity: Cow (Bovine)

Cross-Reactivity (Details): Bovine (100 %)

Characteristics: Rabbit Polyclonal antibody to ABL2 (v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene))
ABL2 antibody [N1N3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ABL2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: IMR32

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.77 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ABL2

Target: ABL2

Alternative Name: ABL2

Background: This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinase. The protein is highly similar to the ABL1 protein, including the tyrosine kinase, SH2 and SH3 domains, and has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Cellular Localization: Cytoplasm , cytoskeleton

Molecular Weight: 128 kDa

Gene ID: 27