ECEL1 antibody

Catalog No. ABIN2854447

This Rabbit Polyclonal antibody specifically detects ECEL1 in WB. It exhibits reactivity toward Human.

Quick Overview for ECEL1 antibody (ABIN2854447)

Target: ECEL1 (Endothelin Converting Enzyme-Like 1 (ECEL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECEL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ECEL1 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to ECEL1 (endothelin converting enzyme-like 1)
ECEL1 antibody [N3C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ECEL1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: ECEL1 transfected 293T

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ECEL1

Target: ECEL1 (Endothelin Converting Enzyme-Like 1 (ECEL1))

Alternative Name: endothelin converting enzyme like 1

Background: This gene encodes a member of the M13 family of endopeptidases. In general, M13 family members are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. This gene is expressed specifically in the central nervous system and its protein localizes predominately to the endoplasmic reticulum or, in trace amounts, to the cell surface. Disruption of this gene in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that this protein plays a critical role in neural regulation of the respiratory system. This gene has multiple pseudogenes.

Cellular Localization: Membrane

Molecular Weight: 88 kDa

Gene ID: 9427

UniProt: O95672