ACOT8 antibody

Catalog No. ABIN2854452

This anti-ACOT8 antibody is a Rabbit Polyclonal antibody detecting ACOT8 in WB. Suitable for Human.

Quick Overview for ACOT8 antibody (ABIN2854452)

Target: ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACOT8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ACOT8 Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit polyclonal antibody to ACOT8 (acyl-CoA thioesterase 8)
ACOT8 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ACOT8. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Molt-4 , Raji , 293T , HepG2 , mouse liver , rat liver

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ACOT8

Target: ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))

Alternative Name: acyl-CoA thioesterase 8

Background: The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. Multiple transcript variants encoding several different isoforms have been found for this gene.

Cellular Localization: Peroxisome

Molecular Weight: 36 kDa

Gene ID: 10005

UniProt: O14734

Pathways: Monocarboxylic Acid Catabolic Process