ACOT8 antibody

Catalog No. ABIN6241571

This Rabbit Polyclonal antibody specifically detects ACOT8 in WB and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ACOT8 antibody (ABIN6241571)

Target: ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACOT8 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ACOT8 Antibody

Immunogen: Synthetic Peptide

Application Details

Application Notes: IF: 1:100. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C,-20 °C

Target Details for ACOT8

Target: ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))

Alternative Name: ACOT8

Background: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N- acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxisome proliferation.

UniProt: O14734

Pathways: Monocarboxylic Acid Catabolic Process