ARSG antibody

Catalog No. ABIN2854468

This Rabbit Polyclonal antibody specifically detects ARSG in WB. It exhibits reactivity toward Human.

Quick Overview for ARSG antibody (ABIN2854468)

Target: ARSG (Arylsulfatase G (ARSG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARSG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARSG Antibody

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to Arylsulfatase G (arylsulfatase G)
Arylsulfatase G antibody [N2C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Arylsulfatase G. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: H1299

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.66 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ARSG

Target: ARSG (Arylsulfatase G (ARSG))

Alternative Name: arylsulfatase G

Background: Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63- kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors.

Cellular Localization: Endoplasmic reticulum

Molecular Weight: 57 kDa

Gene ID: 22901

UniProt: Q96EG1