METTL3 antibody
(1 reference)Quick Overview for METTL3 antibody (ABIN2854497)
Target
See all METTL3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Cross-Reactivity
- Human, Rat
-
Characteristics
-
Rabbit polyclonal antibody to METTL3 (methyltransferase like 3)
METTL3 antibody [N2C2], Internal -
Purification
- Purified by antigen-affinity chromatography.
-
Immunogen
- Recombinant protein encompassing a sequence within the center region of human METTL3. The exact sequence is proprietary.
-
Isotype
- IgG
-
-
anti-Methyltransferase Like 3 (METTL3) (AA 1-156) antibody
METTL3 Reactivity: Human WB, IHC, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Methyltransferase Like 3 (METTL3) antibodyMETTL3 Reactivity: Human, Rat, Mouse WB, IF Host: Rabbit Polyclonal unconjugated
anti-Methyltransferase Like 3 (METTL3) (AA 1-580) antibodyMETTL3 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Methyltransferase Like 3 (METTL3) antibodyMETTL3 Reactivity: Human WB, IF Host: Rabbit Monoclonal unconjugated
anti-Methyltransferase Like 3 (METTL3) (N-Term) antibodyMETTL3 Reactivity: Human, Rat, Mouse, Dog, Rabbit, Horse, Guinea Pig, Cow, Zebrafish (Danio rerio), Bat, Hamster, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Methyltransferase Like 3 (METTL3) (C-Term) antibodyMETTL3 Reactivity: Human, Rat, Mouse, Dog, Rabbit, Horse, Guinea Pig, Cow, Zebrafish (Danio rerio), Goat, Pig, Bat, Hamster, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Methyltransferase Like 3 (METTL3) (Internal Region) antibodyMETTL3 Reactivity: Human, Rat, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Methyltransferase Like 3 (METTL3) (AA 206-255) antibodyMETTL3 Reactivity: Human, Rat, Mouse, Dog, Rabbit, Horse, Guinea Pig, Cow, Zebrafish (Danio rerio), Goat, Pig, Bat, Hamster, Monkey, Xenopus laevis WB Host: Rabbit Polyclonal unconjugated
anti-Methyltransferase Like 3 (METTL3) (AA 503-552) antibodyMETTL3 Reactivity: Human, Rat, Mouse, Dog, Rabbit, Horse, Guinea Pig, Cow, Zebrafish (Danio rerio), Pig, Bat, Hamster, Monkey, Xenopus laevis WB Host: Rabbit Polyclonal unconjugated
anti-Methyltransferase Like 3 (METTL3) (Middle Region) antibodyMETTL3 Reactivity: Human, Rat, Mouse, Dog, Rabbit, Horse, Guinea Pig, Cow, Zebrafish (Danio rerio), Goat WB Host: Rabbit Polyclonal unconjugated
-
-
Application Notes
- WB: 1:5000-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
Comment
-
Positive Control: Molt-4
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
-
Preservative
- Thimerosal (Merthiolate)
-
Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
-
: "METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway." in: Oncology letters, Vol. 19, Issue 4, pp. 3197-3204, (2020) (PubMed).
-
: "METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway." in: Oncology letters, Vol. 19, Issue 4, pp. 3197-3204, (2020) (PubMed).
-
- METTL3 (Methyltransferase Like 3 (METTL3))
-
Alternative Name
- methyltransferase like 3
-
Background
-
This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
Cellular Localization: Nucleus speckle -
Molecular Weight
- 64 kDa
-
Gene ID
- 56339
-
UniProt
- Q86U44
Target
-
