ETV6 antibody

Catalog No. ABIN2854525

This Rabbit Polyclonal antibody specifically detects ETV6 in WB. It exhibits reactivity toward Human.

Quick Overview for ETV6 antibody (ABIN2854525)

Target: ETV6 (Ets Variant 6 (ETV6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETV6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ETV6 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to TEL (ets variant 6)
TEL antibody [N1N3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TEL. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.62 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ETV6

Target: ETV6 (Ets Variant 6 (ETV6))

Alternative Name: ETS variant 6

Background: This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Cellular Localization: Nucleus

Molecular Weight: 53 kDa

Gene ID: 2120

UniProt: P41212