PDZD2 antibody (N-Term)

Catalog No. ABIN2854591

This Rabbit Polyclonal antibody specifically detects PDZD2 in WB. It exhibits reactivity toward Human.

Quick Overview for PDZD2 antibody (N-Term) (ABIN2854591)

Target: PDZD2 (PDZ Domain Containing 2 (PDZD2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDZD2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDZD2 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to PDZK3 (PDZ domain containing 2)
PDZK3 antibody [N1], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human PDZK3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A549

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PDZD2

Target: PDZD2 (PDZ Domain Containing 2 (PDZD2))

Alternative Name: PDZ domain containing 2

Background: Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.

Cellular Localization: Nucleus (By similarity) , Cytoplasm , Endoplasmic reticulum , Processed PDZ domain-containing protein 2: Secreted

Molecular Weight: 302 kDa

Gene ID: 23037

UniProt: O15018