Fukutin antibody
Quick Overview for Fukutin antibody (ABIN2854609)
Target
See all Fukutin (FKTN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human
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Characteristics
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Rabbit Polyclonal antibody to Fukutin (fukutin)
Fukutin antibody [N3C3-2] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human Fukutin. The exact sequence is proprietary.
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Isotype
- IgG
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Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Comment
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Positive Control: H1299 , HeLa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Fukutin (FKTN)
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Alternative Name
- fukutin
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Background
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The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Two transcript variants encoding the same protein have been found for this gene.
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Molecular Weight
- 54 kDa
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Gene ID
- 2218
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UniProt
- O75072
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Pathways
- Regulation of Carbohydrate Metabolic Process
Target
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