FOXM1 antibody (C-Term)

Catalog No. ABIN2854685

The Rabbit Polyclonal anti-FOXM1 antibody has been validated for WB and ChIP. It is suitable to detect FOXM1 in samples from Human. There are 2+ publications available.

Quick Overview for FOXM1 antibody (C-Term) (ABIN2854685)

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXM1 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Grade: KO Validated

Product Details anti-FOXM1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to FOXM1 (forkhead box M1)
FOXM1 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FOXM1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: FOXM1-transfected 293T

Validation: KO/KD, Orthogonal, Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.52 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-FOXM1 antibody (ABIN2854685)

Ju, Huang, Huang, Su: "Identification of thiostrepton as a novel therapeutic agent that targets human colon cancer stem cells." in: Cell death & disease, Vol. 6, pp. e1801, (2016) (PubMed).

Chen, Cheng, Wang, Wu, Chen, Lee: "Up-regulation of FOXM1 by E6 oncoprotein through the MZF1/NKX2-1 axis is required for human papillomavirus-associated tumorigenesis." in: Neoplasia (New York, N.Y.), Vol. 16, Issue 11, pp. 961-71, (2015) (PubMed).

Target Details for FOXM1

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Alternative Name: forkhead box M1

Background: Cellular Localization: Nucleus

Molecular Weight: 84 kDa

Gene ID: 2305

UniProt: Q08050

Pathways: Positive Regulation of Response to DNA Damage Stimulus