EDNRB antibody (N-Term)
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- Target See all EDNRB Antibodies
- EDNRB (Endothelin Receptor Type B (EDNRB))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EDNRB antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human
- Characteristics
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Rabbit polyclonal antibody to ETBR (endothelin receptor type B)
ETBR antibody [N1N2], N-term - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Endothelin B Receptor. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product EDNRB Primary Antibody
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anti-Endothelin Receptor Type B (EDNRB) (AA 409-439), (C-Term) antibody
EDNRB Reactivity: Human, Mouse WB, FACS, IHC (p), IF Host: Rabbit Polyclonal RB19285 unconjugated
anti-Endothelin Receptor Type B (EDNRB) (AA 31-80) antibodyEDNRB Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Endothelin Receptor Type B (EDNRB) (AA 27-101) antibodyEDNRB Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Endothelin Receptor Type B (EDNRB) (C-Term) antibodyEDNRB Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Endothelin Receptor Type B (EDNRB) (N-Term) antibodyEDNRB Reactivity: Human, Dog WB, IHC, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Endothelin Receptor Type B (EDNRB) (N-Term) antibodyEDNRB Reactivity: Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Endothelin Receptor Type B (EDNRB) (AA 1-100) antibodyEDNRB Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Endothelin Receptor Type B (EDNRB) (AA 378-442) antibodyEDNRB Reactivity: Mouse, Rat WB, ELISA, FACS Host: Rabbit Polyclonal unconjugated
anti-Endothelin Receptor Type B (EDNRB) antibodyEDNRB Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
anti-Endothelin Receptor Type B (EDNRB) (C-Term) antibodyEDNRB Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Monkey, Goat, Hamster, Rabbit IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: A431 , H1299
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 50 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- EDNRB (Endothelin Receptor Type B (EDNRB))
- Alternative Name
- endothelin receptor type B (EDNRB Products)
- Background
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The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Three transcript variants encoding two different isoforms have been found for this gene. While both isoforms bind ET1, they exhibit different responses upon binding, suggesting that they may be functionally distinct.
Cellular Localization: Cell membrane - Molecular Weight
- 50 kDa
- Gene ID
- 1910
- UniProt
- P24530
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process
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